Evaluation of estrogenic and thyroid-disrupting activities of targeted CMP3 priority substances: Benzotriazole, Thiocarbamate, Hindered phenols and a brominated organophosphate flame retardant
The transition from tadpole to frog (metamorphosis) and gender differentiation are tightly controlled by the endocrine systems and hormones, where exposure to even low concentrations of certain environmental contaminants can change normal hormone processes that have severe effects on biological development and thus the production of healthy, reproductively capable individuals. We will assess the effects of potential endocrine disrupting CMP3 priority substances, where tadpoles are exposed to environmentally relevant concentrations in water or sediment and assessed for effects on time to metamorphosis, growth, gender, expression of genes involved in development and sexual differentiation and histology of thyroid and gonadal tissue.
Basic view
Metadata Record Information
- File Identifier
- 724ead28-107d-401f-a5e4-f9e8df1ca4b5 XML
- Date Stamp
- 2021-12-15T15:56:44
- Metadata language
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eng; CAN
- Character set
- UTF8
- Hierarchy Level
- Dataset
http://ec.gc.ca
Data identification
- Title
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Evaluation of estrogenic and thyroid-disrupting activities of targeted CMP3 priority substances: Benzotriazole, Thiocarbamate, Hindered phenols and a brominated organophosphate flame retardant
- Date (Publication)
- 2016-09-15
- Date (Creation)
- 2016-09-15
- Status
- On going
- Metadata language
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eng; CAN
- Character set
- UTF8
- Topic category
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- Biota
- Environment
- Health
- Maintenance and Update Frequency
- As needed
- Spatial representation type
- Vector
613-998-0458
Keywords
- Theme
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Chemicals Management Plan, endocrine disruption, laboratory, Silurana tropicalis
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Government of Canada Core Subject Thesaurus
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Pollutants
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ECCC Information Category EN
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Nature and Biodiversity - Contaminants
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Business Functions
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Assess Toxicity, Manage and Monitor for Environmental Presence of Hazardous Substances and Waste
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Assess Toxicity of Substance
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Geography
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Ontario (ON)
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external.theme.EC_Branch
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Science and Technology Branch
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external.theme.EC_Directorate
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Wildlife and Landscape Science
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external.theme.GC_Security_Level
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Unclassified
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- Use Limitation
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Open Government Licence - Canada ( http://open.canada.ca/en/open-government-licence-canada)
- Access Constraints
- Copyright
- Use Constraints
- Copyright
- Begin Date
- 2016-09-15
Extent
))
Ref. system Reference Systems
- Reference system identifier
- EPSG / EPSG:4326 /
Distribution
Distribution Formats
- Distribution format
-
- XLS ( Unknown)
http://ec.gc.ca
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