Evaluation of estrogenic and thyroid-disrupting activities of targeted CMP3 priority substances: Benzotriazole, Thiocarbamate, Hindered phenols and a brominated organophosphate flame retardant

The transition from tadpole to frog (metamorphosis) and gender differentiation are tightly controlled by the endocrine systems and hormones, where exposure to even low concentrations of certain environmental contaminants can change normal hormone processes that have severe effects on biological development and thus the production of healthy, reproductively capable individuals. We will assess the effects of potential endocrine disrupting CMP3 priority substances, where tadpoles are exposed to environmentally relevant concentrations in water or sediment and assessed for effects on time to metamorphosis, growth, gender, expression of genes involved in development and sexual differentiation and histology of thyroid and gonadal tissue.

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Metadata Record Information

File Identifier
724ead28-107d-401f-a5e4-f9e8df1ca4b5 XML
Date Stamp
2021-12-15T15:56:44
Metadata language

eng; CAN
Character set
UTF8
Hierarchy Level
Dataset
Author
  Government of Canada; Environment and Climate Change Canada - Environment and Climate Change Canada ( Public inquiries centre )
Fontaine Building 12th floor, 200 Sacré-Coeur Blvd , Gatineau , Quebec , K1A 0H3 ,
1-800-668-6767
http://ec.gc.ca
 

Data identification

Date (Publication)
2016-09-15
Date (Creation)
2016-09-15
Status
On going
Metadata language

eng; CAN
Character set
UTF8
Topic category
  • Biota
  • Environment
  • Health
Maintenance and Update Frequency
As needed
Spatial representation type
Vector
Author
  Government of Canada; Environment and Climate Change Canada - Stacey A Robinson ( Research Scientist )
1125 Colonel By Drive , Ottawa , Ontario , K1S5B6 , Canada
613-990-9749
613-998-0458
Custodian
  Government of Canada; Environment and Climate Change Canada - Pamela Martin ( Section Chief )
867 Lakeshore Road , Burlington , Ontario , L7S1A1 , Canada
905-336-4879

Keywords

Theme

  • Chemicals Management Plan, endocrine disruption, laboratory, Silurana tropicalis

Government of Canada Core Subject Thesaurus

  • Pollutants

ECCC Information Category EN

  • Nature and Biodiversity - Contaminants

Business Functions

  • Assess Toxicity, Manage and Monitor for Environmental Presence of Hazardous Substances and Waste

  • Assess Toxicity of Substance

Geography

  • Ontario (ON)

external.theme.EC_Branch

  • Science and Technology Branch

external.theme.EC_Directorate

  • Wildlife and Landscape Science

external.theme.GC_Security_Level

  • Unclassified
 
Use Limitation

Open Government Licence - Canada ( http://open.canada.ca/en/open-government-licence-canada )

Access Constraints
Copyright
Use Constraints
Copyright
Begin Date
2016-09-15

Extent

N
S
E
W
thumbnail


 
 

Ref. system Reference Systems

Reference system identifier
EPSG / EPSG:4326 /
 

Distribution

Distribution Formats

Distribution format
  • XLS ( Unknown )

 
Distributor
  Government of Canada; Environment and Climate Change Canada - Environment and Climate Change Canada ( Public inquiries centre )
Fontaine Building 12th floor, 200 Sacré-Coeur Blvd , Gatineau , Quebec , K1A 0H3 ,
1-800-668-6767
http://ec.gc.ca
 
 

Overviews

N
S
E
W
thumbnail


Keywords

Chemicals Management Plan, endocrine disruption, laboratory, Silurana tropicalis
Business Functions
Assess Toxicity of Substance Assess Toxicity, Manage and Monitor for Environmental Presence of Hazardous Substances and Waste
ECCC Information Category EN
Nature and Biodiversity - Contaminants
Government of Canada Core Subject Thesaurus
Pollutants
external.theme.EC_Branch
Science and Technology Branch
external.theme.EC_Directorate
Wildlife and Landscape Science
external.theme.GC_Security_Level
Unclassified

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