Effects of brominated emerging flame retardants in juvenile rainbow trout

In this study, the chronic effects of two emerging brominated flame retardants, 1,2-bis(2,4,6-tribromophenoxy)ethane(BTBPE) and 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB) were evaluated in diet exposed juvenile rainbow trout (Oncorhynchus mykiss). Fish uptake was measured after 28-d of exposure. Liver gene transcription analysis using RNA-sequencing was also performed, complemented by qRT-PCR to measure transcription levels of genes related to the immune response in the liver and the head kidney. Lysozyme enzymatic activity was also measured in head kidneys of exposed fish.


Results are published in a peer-reviewed scientific publication. Citation:

Giraudo, M., Douville, M., Letcher, R. J., & Houde, M. (2017). Effects of food-borne exposure of juvenile rainbow trout (Oncorhynchus mykiss) to emerging brominated flame retardants 1,2-bis(2,4,6-tribromophenoxy)ethane and 2-ethylhexyl-2,3,4,5-tetrabromobenzoate. Aquatic Toxicology (Amsterdam, Netherlands), 186, 40-49. doi.org/10.1016/j.aquatox.2017.02.023

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Metadata Record Information

File Identifier
ae0c8672-10ba-4f72-a8b4-c4e8f242793b XML
Date Stamp
2023-05-30T19:24:24
Metadata language

eng; CAN
Character set
UTF8
Hierarchy Level
Non geographic dataset
Point of contact
  Government of Canada; Environment and Climate Change Canada; Science and Technology Branch / Water Science and Technology / Aquatic Contaminants Research Division - ACRD Data Management Team
867 Lakeshore Road , Burlington , Ontario , L7S 1A1 , Canada
 

Data identification

Date (Publication)
2021-11-05
Date (Creation)
2017-02-22
Status
Completed
Metadata language

eng; CAN
Character set
utf8
Topic category
  • Biota
  • Environment
Maintenance and Update Frequency
As needed
Principal investigator
  Government of Canada; Environment and Climate Change Canada; Science and Technology Branch / Water Science and Technology / Aquatic Contaminants Research Division - Maeva Giraudo ( Research associate )
105 McGill street , Montreal , Quebec , H2Y 2E7 , Canada
Collaborator
  Government of Canada; Environment and Climate Change Canada; Science and Technology Branch / Water Science and Technology / Aquatic Contaminants Research Division - Dr. Magali Houde ( Research scientist )
105 McGill street , Montreal , Quebec , H2Y 2E7 , Canada

Keywords

Theme

  • rainbow trout (Oncorhynchus mykiss)

  • flame retardants

  • 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE)

  • 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB)

  • immune response

  • lysozyme

  • RNA-sequencing

  • Genomics Research and Development Initiative (GRDI)

  • gene transcription

  • chronic toxicity

  • food-borne exposure

  • Strategic Technology Applications of Genomics in the Environment (STAGE)

  • Chemical Management Plan (CMP)

Government of Canada Core Subject Thesaurus

  • Toxicology

  • Toxic substances

  • Freshwater fish

  • Fish

  • Biology

  • Genomics

  • Chemistry

  • Aquatic animals

Environment Canada - Program

  • 1.2.1. Water Quality and Aquatic Ecosystems Health

Business Functions

  • Assess Toxicity, Manage and Monitor for Environmental Presence of Hazardous Substances and Waste

  • Assess Toxicity of Substance

Government of Canada Departments and Agencies

  • Environment and Climate Change Canada

Branch

  • Science and Technology Branch

Directorate

  • Water Science and Technology

Program (PAA)

  • 1.2.1. Water Quality and Aquatic Ecosystems Health

Environment Canada - GC Security Classification

  • Unclassified
 
Use Limitation

Open Government Licence - Canada ( http://open.canada.ca/en/open-government-licence-canada )

Access Constraints
License
Use Constraints
License
Begin Date
2017-02-22

Extent

N
S
E
W
thumbnail


 
 

Ref. system Reference Systems

Reference system identifier
http://www.epsg-registry.org / EPSG:4326 /
 

Distribution

Distribution Formats

Distribution format
  • CSV ( unknown )

 
Distributor
  Government of Canada; Environment and Climate Change Canada - Public Inquiries Centre
Fontaine Building 12th floor, 200 Sacré-Coeur Blvd , Gatineau , Quebec , K1A 0H3 , Canada
1-800-668-6767
 
 

Overviews

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W
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Keywords

1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE) 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB) Chemical Management Plan (CMP) Genomics Research and Development Initiative (GRDI) RNA-sequencing Strategic Technology Applications of Genomics in the Environment (STAGE) chronic toxicity flame retardants food-borne exposure gene transcription immune response lysozyme rainbow trout (Oncorhynchus mykiss)
Branch
Science and Technology Branch
Business Functions
Assess Toxicity of Substance Assess Toxicity, Manage and Monitor for Environmental Presence of Hazardous Substances and Waste
Directorate
Water Science and Technology
Environment Canada - GC Security Classification
Unclassified
Environment Canada - Program
1.2.1. Water Quality and Aquatic Ecosystems Health
Government of Canada Core Subject Thesaurus
Aquatic animals Biology Chemistry Fish Freshwater fish Genomics Toxic substances Toxicology
Government of Canada Departments and Agencies
Environment and Climate Change Canada
Program (PAA)
1.2.1. Water Quality and Aquatic Ecosystems Health

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