Metformin: Environmental fate and effects study
This study will determine the toxic effect the pharmaceutical metformin has on an aquatic environment. Chronic exposures were conducted at Lake 114 located at the International Institute for Sustainable Development-Experimental Lakes Area (IILSD-ELA) in Ontario, Canada. Three concentrations of metformin were used to study the effects on the adult and embryo life stages of the fathead minnow (Pimephales promelas) as well as the effect on the food chain within the mesocosms. Water samples for basic chemistry and nutrient samples were collected throughout the exposures. There is currently one publication and the authors plan to submit two more manuscripts from this research project.
All data are a part subject of a publication containing method details, full QA/QC, interpretations and conclusions. Citation: Nielsen, K. M., DeCamp, L., Birgisson, M., Palace, V. P., Kidd, K. A., Parrott, J. L., McMaster, M. E., Alaee, M., Blandford, N., & Ussery, E. J. (2022). Comparative Effects of Embryonic Metformin Exposure on Wild and Laboratory-Spawned Fathead Minnow (Pimephales promelas) Populations. Environmental science & technology, 56(14), 10193–10203. doi.org/10.1021/acs.est.2c01079
Basic view
Metadata Record Information
- File Identifier
- ab2f0345-a1f0-488b-a2c2-13cb35d7c82c XML
- Date Stamp
- 2023-11-29T20:22:43
- Metadata language
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eng; CAN
- Character set
- UTF8
- Hierarchy Level
- Dataset
Data identification
- Date (Creation)
- 2022-05-22
- Date (Publication)
- 2023-05-31
- Status
- On going
- Metadata language
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eng; CAN
- Character set
- utf8
- Topic category
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- Environment
- Maintenance and Update Frequency
- As needed
Keywords
- Theme
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metformin
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fathead minnow (Pimephales promelas)
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phytoplankton
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zooplankton
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ecotoxicology
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pharmaceuticals
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freshwater
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Chemicals Management Plan (CMP) of Health Canada
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New Substances Assessment and Control Bureau (NSACB)
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Government of Canada Core Subject Thesaurus
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Environment
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Water
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Business Functions
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Assess Toxicity of Substance
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Assess Toxicity, Manage and Monitor for Environmental Presence of Hazardous Substances and Waste
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Branch
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Science and Technology Branch
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Directorate
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Water Science and Technology
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Environment Canada - Program
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1.2.1. Water Quality and Aquatic Ecosystems Health
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GC Security Level
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Unclassified
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Canada/US States and Provinces
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Ontario
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- Use Limitation
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Open Government Licence - Canada ( http://open.canada.ca/en/open-government-licence-canada )
- Access Constraints
- License
- Use Constraints
- License
- Begin Date
- 2019-05-22
- End Date
- 2019-07-23
Extent
Ref. system Reference Systems
- Reference system identifier
- https://epsg.io / EPSG:4326 /
Distribution
Distribution Formats
- Distribution format
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CSV
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Unknown
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CSV
(
Unknown
)